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Symbol Name ID |
Bax
BCL2-associated X protein MGI:99702 |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased circulating IgA level |
Decreased circulating IgG level |
Decreased circulating IgG2 level |
Defective B cell differentiation |
Abnormal B cell count |
Decreased proportion of CD4-positive helper T cells |
T lymphocytopenia |
Lymphopenia |
Leukemia |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Lymphoma |
Hodgkin lymphoma |
Non-Hodgkin lymphoma |
| Disease(s) Associated with BAX | ||||||||||||||
| acute lymphoblastic leukemia | ||||||||||||||
| ataxia telangiectasia |
| Mouse Phenotypes | increased thymocyte number |
enlarged spleen |
increased transitional stage B cell number |
increased B cell number |
abnormal plasma cell morphology |
increased IgA level |
increased IgE level |
increased IgG1 level |
increased IgG2a level |
increased IgG level |
increased IgM level |
increased immunoglobulin level |
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| Availability | Mouse Genotype | ||||||||||||
| Baxtm1Sjk/Baxtm1Sjk | |||||||||||||
| Tg(Igk-V21-Bax)1967Bvn/0 | |||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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